EPoS trial has started
After one year with preparations, the European Polyp Surveillance Trial (EPoS) has started patient recruitment. The EPoS study will include 30,000 patients over the next three years. Aim of the study is to find better surveillance intervals for patients with colorectal polyps.
First patient enrolment
The first six patients were randomized at Sørlandet Hospital in Kristiansand, Norway, in May 2015. In June, Oslo University Hospital started to enrol their first patients, and in the first week of August, Poland and Spain started to enrol patients.
The EPoS study is a large multinational project which is financed by multiple sources in the participating countries.
Latest publicationsBrunsell et al. 2019. High concordance and negative prognostic impact of RAS/BRAF/PIK3CA mutations in multiple resected colorectal liver metastases. Clin. Colorectal Cancer [Online ahead of print] Sveen et al. 2019. Predictive modeling in colorectal cancer: time to move beyond consensus molecular subtypes. Ann. Oncol. 30(11): 1682-1685 Miranda et al. 2019. Cancer stemness, intratumoral heterogeneity, and immune response across cancers. PNAS 116(18): 9020-9029 Burocziova et al. 2019. Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon. Cell Death. Dis. 10(11): 818
Eilertsen et al. 2019. Technical differences between sequencing and microarray platforms impact transcriptomic subtyping of colorectal cancer. Cancer Lett. [Epub ahead of print] All publications