First EPoS study paper published
The leading scientific journal «Endoscopy» has today released the first paper from the European Polyp Surveillance (EPoS) study group. The aim of the EPoS study is to find better surveillance intervals for patients with colorectal polyps.
The paper describes the rationale and design of the EPoS trials and gives a comprehensive overview of important features and considerations in the planning and conduction of the EPoS initiative.
The EPoS trials investigate the optimal surveillance strategy for patients with colorectal polyps. Patients are randomized to different surveillance intervals with colonoscopy. The primary endpoint is incidence of colorectal cancer after 10 years of follow-up.
EPoS is the largest randomized trial in its field. Centres in Norway, Sweden, Spain, Poland, the Netherlands and other European countries are contributing in the trial.
Please access the paper Rationale and design of the European Polyp Surveillance (EPoS) trials.
Latest publicationsBurocziova et al. 2019. Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon. Cell Death. Dis. 10(11): 818
Eilertsen et al. 2019. Technical differences between sequencing and microarray platforms impact transcriptomic subtyping of colorectal cancer. Cancer Lett. [Epub ahead of print] Lopes et al. 2019. Digital image analysis of multiplex fluorescence IHC in colorectal cancer recognizes the prognostic value of CDX2 and its negative correlation with SOX2. Lab. Invest. [Epub ahead of print] Dienstmann et al. 2019. Relative contribution of clinicopathological variables, genomic markers, transcriptomic subtyping and microenvironment features for outcome prediction in stage II/III colorectal cancer. Ann. Oncol. [Epub ahead of print] Totland et al. 2019. Regulation of gap junction intercellular communication by connexin ubiquitination: physiological and pathophysiological implications. Cell. Mol. Life Sci. [Epub ahead of print] All publications