Official opening of the K.G. Jebsen Colorectal Cancer Research Centre
The K.G. Jebsen Colorectal Cancer Research Centre was officially opened on the 28th of August by the chair of the Jebsen Foundation’s board of directors, Hans Peter Jebsen. Prof. Ragnhild A. Lothe will lead the Centre together with the interdisciplinary PI team consisting of Prof. Michael Bretthauer (gastroenterologist), Prof. Arild Nesbakken (surgeon), Prof. Kjell Tveit (oncologist), and ass. Prof. Rolf I. Skotheim (bioinformatician).
From left: Hans Peter Jebsen, Sigbjørn Smeland and Ragnhild A. Lothe
The event was held at Holmenkollen Park Hotel for all the members of the new Centre as well as invited guests. Present from the board of directors of the Foundation were also Birger Magnus and Borger Lenth, as well as the general manager of the Foundation, Kåre Rommetveit, who presented the Foundation’s strategy for supporting medical research.This is the only Jebsen Centre in Oslo that has Oslo University Hospital as its main host institution. Prof. Sigbjørn Smeland, head of the hosting Division of Cancer, Surgery and Transplantation, said in his talk that the Centre is an excellent example of how to organize and succeed in translational research within a Comprehensive Cancer Centre. The rector of the University of Oslo, Prof. Ole Petter Ottersen, underlined the many challenges in building real integrated research among disciplines, but also the necessity of doing so to combat global health challenges such as colorectal cancer, a disease which kills seven hundred thousand individuals annually.The Centre addresses both early detection strategies and novel treatment strategies, and got off to a flying start with an article published by the Bretthauer group in NEJM on the same day.
The Centre’s guest lecturer for the day, Prof. Hans Olav Adami from Harvard, presented his ideas on why Harvard is ranked as a world leading institution of research and which factors we need to address in Scandinavia. Among others, he pointed out the importance of using the strength that lies in the public health system.
The director of Research and Innovation of the South-Eastern Norway Regional Health Authority, John Torgils Vaage, congratulated on the opening of the Centre and explained that excellent clinical research argued strongly for prioritization of increased research funding from the Health Authority.
Latest publicationsBrunsell et al. 2019. High concordance and negative prognostic impact of RAS/BRAF/PIK3CA mutations in multiple resected colorectal liver metastases. Clin. Colorectal Cancer [Online ahead of print] Sveen et al. 2019. Predictive modeling in colorectal cancer: time to move beyond consensus molecular subtypes. Ann. Oncol. 30(11): 1682-1685 Miranda et al. 2019. Cancer stemness, intratumoral heterogeneity, and immune response across cancers. PNAS 116(18): 9020-9029 Burocziova et al. 2019. Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon. Cell Death. Dis. 10(11): 818
Eilertsen et al. 2019. Technical differences between sequencing and microarray platforms impact transcriptomic subtyping of colorectal cancer. Cancer Lett. [Epub ahead of print] All publications