Lothe and Bretthauer substantially supported by FRIPRO
Lothe and Bretthauer are given support for the projects "Modeling tumor heterogeneity in colorectal cancer management" and "COLOSS - COLOn Screening and Surveillance: Comparative Effectiveness of Colorectal Cancer Screening and Surveillance" respectively.
The Research Council of Norway and Norway’s research institutions are providing a total of NOK 1 billion to 46 FRIPRO Toppforsk projects (FRIPRO – “Frie prosjektmidler”). Each project will receive NOK 15–25 million over a four-to-five-year period. FRIPRO is an open competitive arena for all research areas and disciplines, where there are no thematic guidelines and no requirements relating to the applicability or immediate utility of the research. The competition in FRIPRO is tough, and only the best researchers with particularly good projects and very well-written proposals have a chance of succeeding.
University of Oslo and Oslo University Hospital based research groups led by Ragnhild A. Lothe from the Department of Molecular Oncology and Michael Bretthauer from the Clinical Effectiveness Research Group are among the successful applicants.
Lothe and Bretthauer are given support for the projects “Modeling tumor heterogeneity in colorectal cancer management” and “COLOSS – COLOn Screening and Surveillance: Comparative Effectiveness of Colorectal Cancer Screening and Surveillance” respectively. Together with the Research Council, the Medical Faculty from the University of Oslo, support their research through TOPPFORSK, spanning from cancer prevention to genomic tumor heterogeneity.
Funding for Toppforsk projects is being provided in a joint effort by Norway’s universities and other research institutions and the Ministry of Education and Research and allocated via the Research Council. This is the third such joint funding initiative for the FRIPRO scheme for independent projects. Funding is only being allocated to projects that have received the highest score after review by international referee panels. The universities themselves have selected projects for funding from the list of top-ranked projects at their institution. All of the universities have been given funding for at least one Toppforsk project. University colleges, research institutions and the regional health authorities are participating in the joint funding initiative for the first time.
About Bretthauer’s project: Michael Bretthauer awarded Toppforsk 2016
About Lothe’s project (in Norwegian): Forskningsmidler til tarmkreftprosjekt
From the UiO:Life Science home page (in Norwegian): Toppforsk-midlar til sterke livsvitskapsmiljø ved UiO
Read more about this prestigious grant from the Norwegian Research Council home page:
English version: NOK 1 billion to top-notch researchers
Norwegian version: En milliard til sterke forskningsmiljøer
Latest publicationsSveen et al. 2019. Predictive modeling in colorectal cancer: time to move beyond consensus molecular subtypes. Ann. Oncol. 30(11): 1682-1685 Miranda et al. 2019. Cancer stemness, intratumoral heterogeneity, and immune response across cancers. PNAS 116(18): 9020-9029 Burocziova et al. 2019. Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon. Cell Death. Dis. 10(11): 818
Eilertsen et al. 2019. Technical differences between sequencing and microarray platforms impact transcriptomic subtyping of colorectal cancer. Cancer Lett. [Epub ahead of print] Lopes et al. 2019. Digital image analysis of multiplex fluorescence IHC in colorectal cancer recognizes the prognostic value of CDX2 and its negative correlation with SOX2. Lab. Invest. [Epub ahead of print] All publications